regenerative support
comfort in gynecological tissues.
gynecological tissue regeneration.
What is
IntraGraft® FAT
A sterile, single-use kit for the processing and minimal manipulation of adipose tissue, IntraGraft® FAT is a complete solution that includes all the instruments required for a full regenerative medicine procedure.
The treatment can be performed in an outpatient clinic or operating room, under local anesthesia, in just a few minutes.
Indications and
Clinical Benefits
IntraGraft® FAT is indicated for the treatment of:
• Vulvar lichen sclerosus and other chronic vulvar dystrophies
• Genitourinary syndrome of menopause (GSM)
• Post-surgical and post-traumatic vulvovaginal atrophy
• Scarring and tissue retraction following episiotomy or pelvic surgery
• Dyspareunia and chronic pelvic pain of inflammatory or neuropathic origin
Clinical benefits include:
• Local anti-inflammatory action (↑ IL-10, ↓ TNF-α)
• Restoration of tissue trophism and hydration
• Promotion of neovascularization and improved tissue elasticity
• Reduction in pain and improvement in sexual function
• Minimally invasive procedure with high tolerability and safety profile
Centrifugation vs.
Mechanical Filtration
IntraGraft® FAT employs a gravity decantation and progressive filtration system to obtain MicroFat and NanoFat—concentrated, fluid forms of adipose tissue.
Mechanical filtration preserves cell viability and enables effective injection even through very fine needles (27–30G).
Key Features of the
IntraGraft® Fat Technique
Minimally traumatic harvesting
→ Reduces patient discomfort and preserves cellular integrity.
Targeted superficial collection
→ Superficial subcutaneous fat is biologically richer in ADSCs.
Standardized technique
→ Repeatable protocol, even for operators without liposuction experience.
Small-sized cellular clusters
→ Promote graft retention and integration at the target site.
Minimal manipulation
→ No centrifugation or complex devices → maximized cell viability, quick procedure, and reduced costs.
Low complication rate
→ Reduced risk of hematomas, seromas, infections, and tissue irregularities.
Optimal injectability of the tissue
→ Smooth consistency, easily injectable with fine needles or cannulas for minimally invasive
treatments.
Outpatient and accessible
→ Fully executable in an outpatient surgical setting or operating room with a sterile, single-use,
all-in-one kit.
