Anti-inflammatory Effect:
→ Mesenchymal stem cells (ADSCs) modulate the inflammatory response by secreting anti-inflammatory cytokines (IL-10, TGF-β). They reduce pain and swelling in periarticular and periprosthetic tissues, improving load tolerance in joints affected by osteoarthritis or traumatic processes. They also promote macrophage transition from the pro-inflammatory (M1) to the regenerative (M2) phenotype, contributing to inflammation resolution.

Regenerative Effect:
→ Mesenchymal stromal cells stimulate proliferation and differentiation of resident cells in bone, cartilage, and tendon tissues damaged by trauma or degeneration. They promote angiogenesis and remodeling of the extracellular matrix, improving the structural and functional quality of tissues surrounding prosthetic or injured areas.

Analgesic Effect:
→ The combined anti-inflammatory and regenerative action leads to significant pain reduction, even in chronic conditions related to osteoarthritis or post-surgical trauma. This results in a reduced need for anti-inflammatory drugs or corticosteroid injections.

Immunomodulatory Effect:
→ ADSCs modulate immune cell activity (lymphocytes, macrophages, dendritic cells), attenuating inflammatory and autoimmune responses, useful in degenerative joint diseases or inflammatory reactions associated with prosthetic and traumatic surgery.

Functional Improvement:
→ The use of mesenchymal cells is associated with increased joint range of motion, improved muscle strength and overall limb functionality, and reduced post-operative or post-trauma recovery times.